Faʻaaogaina Endocrinology: Le Gut ma le "Chemo-Brain" Fesoʻotaʻiga

E te lagona:

• Naua pe lagona e pei o le vomiting?
• Mataʻutia, itagofie, pe popole?
• Le mautonu maso tumau?
• O le alaga vaivai ina ua mavae le ono po o le sili atu itula o moe?
• Le fiafia po o le leai o se uunaiga?

Afai o loʻo e feagai ma nisi o nei tulaga, o le a iai se mea e ono sese i lou faʻaoga ma le faiʻai i totonu o lou tino.

Fagu Gain-Brain

O le feʻau ma le faiʻai e fesoʻotaʻi ma lima ao latou lafoina faʻamaufaʻailoga i tua ma mautinoa e amata lelei le gaoioi o le tino o le tagata. O le ū e mautinoa o loʻo faʻatino lelei lona tino atoa, le endocrin system, ma le siama. E ui o le faiʻai e mautinoa o loʻo galue lona neurology ae o loʻo tuʻuina atu foi faʻamaumauga i le tino atoa ma faʻamautinoa e tufatufaina atu hormones i totoga taua.

Chemo-Brain ma le Gut Connection

E ui lava e tāua le fesoʻotaʻi ma le faiʻai ile tino maloloina, ae peitaʻi, a oʻo mai i se tagata o loʻo maua i le kanesa atonu e iai se ―chemo-faiʻai ma manaʻoga fesoʻotaʻiga pe a latou maua togafitiga mai le chemotherapy. Talu ai o le chemotherapy o le masani masani o tausiga mo le togafitia o le kanesa e ala i le tuʻufaʻatasia tumau o vailaau faʻamalosi e fasiotia ai sela o le kanesa. I le lalolagi atoa, e sili atu i le 100 ituaiga o kanesa e mafai ona osofaia ai siama ma salalau atu i totonu o totoga eseese ma fusi i le tino o le tagata. Ae faimai foi suʻesuʻega mai le CDC, na taʻua ai o le kanesa o le mafuaaga lona lua o le oti i le US.

E iai tele faʻamatalaga e uiga i le chemotherapy faia i le tino talu chemotherapy galue e ala i le taofia o le kanesa sela mai faʻateleina poʻo le tuai lemu le fua o le kanesa sela tupu. Ae paga lea, e ui o le chemotherapy e mafai ona faʻatatau i sela o le kanesa ua tupuolaola, ae mafai foi ona fasiotia sela maloloina o le tino. A osofaʻia sela maloloina e le chemotherapy, o sela e mafai ona mafua ai se umi lisi o tiga tiga aʻafiaga. Mo se faʻataʻitaʻiga, o sela epithelial i le GI tract e mafai ona faʻaleagaina, ma mafai ai ona mafua ai le tele o gasegase kanesa e taofi muamua le togafitiga o chemo.

In se suʻesuʻega talu ai nei lea sa lomia i Frontier i le Pharmacology, na faaalia ai sa maua e saienitisi se auala fou e laveai ai le chemotherapy lea e mafai ona osofaia ai siama matautia i le tino ae tuua ai na o le ola maloloina. Faatasi ai ma lenei auala, e mafai ona maua ai sina faʻamoemoe e ala ile faʻatagaina o fomaʻi e tuʻu i lalo metotia o togafitiga ole chemo e faʻaititia ai tagata mamaʻi o loʻo mafatia i ni faʻamaʻi leaga o le chemo, e mafai ona faʻateleina ai le faʻamalieina ma faʻaleleia atili ai le faʻavasega mo tagata mamaʻi.

In se suʻesuʻega talu ai nei, ua maua e se saienitisi suʻesuʻe mai le Iunivesite o Ohio State se tali talafeagai e fesoasoani ai e faaleleia le gastrointestinal and cognitive effects effects that were caused by chemotherapy. E tusa ai ma le suʻesuʻega, o le faʻataʻitaʻiga o loʻo faʻaalia ai pe faapefea ona faʻaogaina le sootaga i le va o faʻataʻitaʻiga ma le faiʻai i togafitiga o chemotherapy. Na maua iʻuga pe faapefea ona suia atoatoa le fualaau oona i le microbiome o le tagata. Na latou fai mai na suia le siama o le tino ma le tino ae o le toto ma le faiʻai i le tino ua faaalia ai faailoga o le mumū-mafua ai le vaivai ma le faaletonu o le mafaufau. Afai o togafitiga o le chemo e mafua ai le mumū o loʻo i totonu o le neurological system, e mafai ona faʻaogaina le faʻaogaina o le tino atoa ma le faʻaleagaina o colonic ma siama ile homeostasis i le tino.

I le chemotherapy, e mafai ona mafua ai permeability gofie. E mafai ona faʻaosofia ai le malosi o le tino i le tino i le soona faʻagaoioia ma le faʻailo o sela o le faiʻai ina ia susunuina aʻo avea foʻi ma mafuaʻaga o le "chemo faiʻai." Chemo-faiʻai ua faʻamatalaina o le mafaufau le atoatoa ma mafua ai le tagata i le mafaufau fogginess e mafai ona nofo mo masina pe oʻo foi i tausaga talu ona uma le kanesa. Maofa i le lenei fou fou, chemo-brain ua afaina ai le sili atu ma le afa o tagata na sao mai le kanesa a o avea ma mea masani ona o kanesa togafitiga mafai faʻalauteleina le gasegase olaga atoa.

Faʻatasi ai ma lenei ituaiga o suʻesuʻega, e mafai ona faʻamalamalamaina ai le auala e mafai ai ona sili atu le afaina o le soifua maloloina o le microbiome, nai lo le digestive tract, talu ai ona o le manaʻoga e taua tele lona sao i isi faiga uma i le tino, aemaise lava i le puipuiga ma le popole. . I le tilotilo atu le molimau o loʻo iai, latou te faʻaalia le faʻafefea ona fesoʻotaʻi le soifua maloloina ma le soifua manuia o le manava o le tino ma le faiʻai. E mafai ona taitai atu ai i sili lelei togafiti mo le tele o gasegase kanesa e ala i le faalauiloaina o se aoga siama tuufaatasiga mo le manava ma mafai puipuia mai soʻo se neuroinflammation e faʻaititia ai soʻo se faʻailoga o chemo-faiai.

Faʻamatalaga Faʻamatalaga Faʻamatalaga ma Talakalame

E saʻo lava Hippocrates ina ua ia taʻua e faapea "o faamaʻi uma e amata mai i le manava." O faʻamatalaga na saunia ai le ala mo le tele o fomaʻi faʻamalositino e fesoasoani ai i le tele o gasegase kanesa. I le faʻaopopoina o ni meaʻai e teteʻe ai le mafaufau i meaʻai a se tagata pei o le taumafataga a le Metitirani pe oʻo foʻi i se meaʻai ole ketogenic e sili ona lelei mo tagata mamaʻi ole kanesa. E fautuaina mo tagata mamaʻi ile kanesa ina ia faʻateleina a latou taumafa o le prebiotics ma le probiotic-rich food. Ua faʻamaonia o probiotics ma prebiotics mafai ona fesoasoani e faaitiitia o le aʻafiaga o aʻafiaga e aʻafia ai le tele o tagata gasegase e oʻo i le taimi oa latou togafitiga o le kemisi. Faʻamatalaga ma mea faʻapitoa, o meaʻai laoa-e mafai ona faʻamalosi ma faʻaumatia ina ia maua ai e tagata ia siama aoga ma faʻamaʻi o loʻo nonofo i le gutu ma mafai ona faʻaleleia le faʻaogaina o le microbiome.

iʻuga

Faatasi ai ma le manava ma le faiʻai fesoʻotaʻiga, latou te galulue faʻatasi i le mautinoa o le tino o gaioiga saʻo. A o chemo-faiʻai, peitaʻi, e mafai ona mafua ai faʻaleagaina i le tino e ala i le faʻaleagaina o le tino atoa tino ala chemotherapy. I le faʻaopopoina o probiotics ma prebiotics i le kanesa o meaʻai meaʻai e mafai ona fesoasoani ia latou ia maua ia latou tino meaʻai ma mea aoga aoga latou te manaʻomia. Nisi oloa e aoga i le tino e ala i le lagolagoina e le gata o le totoa ae ia mautinoa foi le faiʻai o loʻo lagolagoina foi.

O le lautele o a tatou faʻamatalaga e faʻamapulaʻa i fomaʻi, musikalokeletal, ma mataupu tau le soifua maloloina o le tino poo mataupu tau vailaʻau faʻaleafugaga, autu, ma talatalanoaga. Matou te faʻaogaina togafitiga faʻalesoifua maloloina e togafitia ai manuʻa poʻo faʻalavelave o le masukulekelet system. O lo matou ofisa ua faia se taumafaiga talafeagai e tuʻuina atu faʻamaoniga lagolago ma ua faʻamaonia suʻesuʻega suʻesuʻega talafeagai poʻo suʻesuʻega e lagolago ai o matou pou. Matou te faia foi ni kopi o suʻesuʻega suʻesuʻe suʻesuʻe e avanoa i le komiti poʻo le lautele pe a talosagaina. Ina ia toe talanoaina le mataupu o loʻo i luga, faamolemole ia lagona le saolotoga e fesili atu ia Dr. Alex Jimenez pe faʻafesoʻotaʻi mai i matou 915-850-0900.

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mau:

Arora, Malika, et al. 'Aʻafiaga o Probiotics ma Prebiotics i luga o le Kanesa o le Kanesa: Malamalamaaga Malamalama ma Faʻataʻitaʻiga Lumanaʻi. Latest TOC RSS, Bentham Science Publishers, 1 Ianuari 1970, www.ingentaconnect.com/content/ben/cctr/2019/00000015/00000001/art00005.

Caldwell, Emily. 'O Se Fesoʻotaʻiga Gut-Brain ono' Chemo Brain ' Fomaʻi Faʻamatalaga - Faʻamatalaga Faʻapitoa mo Suesuega ma le Soifua Maloloina, Medical Xpress, 23 Oke. 2019, medicalxpress.com/news/2019-10-gut-brain-chemo-brain.html.

Caldwell, Emily. ―The Gut May Be the Ticket to Reducing Chemo's Side effects. '' Fomaʻi Faʻamatalaga - Faʻamatalaga Faʻapitoa mo Suesuega ma le Soifua Maloloina, Medical Xpress, 11 Nov 2019, medicalorot.com/news/2019-11-gut-ticket-chemo-side-effects.html?utm_source=nwletter&utm_ Medium=email&utm_campaign=daily-nwletter.

Loman, BR, et al. NeCurootherapy-Faʻaosoina Neuroinflammation e fesoʻotaʻi ma faʻalavelaveina Colonic ma siama Homeostasis i Tamaʻitaʻi Isumu. Natura Natura, Group Publishing Group, 11 Nov. 2019, www.nature.com/articles/s41598-019-52893-0.

Neumann-Raizel, Hagit, et al. 2-APB ma le CBD-Mediated Targeting of Charged Cytotoxic Compounds In Tumor Cells Fautuaina le Aofia ai o TRPV2 Channels. ' tapulaa, Tuaʻoi, 17 Setema 2019, www.frontiersin.org/articles/10.3389/fphar.2019.01198/full.

aufaigaluega, Saienitisi X. "Chemo Brain" mafua mai i le le atoatoa i le tolu Ituaiga o Brain Cells, Suesuega Mauaina. Fomaʻi Faʻamatalaga - Faʻamatalaga Faʻapitoa mo Suesuega ma le Soifua Maloloina, Mental Health, 6 Tesema 2018, medicalxpress.com/news/2018-12-chemo-brain-malfunction-cells.html.

aufaigaluega, Saienitisi X. '' Tomai Faʻapitoa Aʻoaʻoga O Maʻi Kanesa ma Tuua Naʻua Tagata Maloloina. ' Fomaʻi Faʻamatalaga - Faʻamatalaga Faʻapitoa mo Suesuega ma le Soifua Maloloina, Medical Xpress, 27 Novema 2019, medicalxpress.com/news/2019-11-technique-cancer-cells-healthy.html.

Au, DFH. '' Fou Suʻesuʻega - Fofo Fofo i Chemotherapy Mamanu mo le Soifua Maloloina, 2 Ianuari 2020, blog.designsforhealth.com/node/1179.

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Soifua Maloloina Faʻaonapo nei- Esse Quam Videri

O le Iunivesite e ofoina atu le tele o ituaiga fomaʻi mo fomaʻi galue ma faʻataʻitaʻiga. O la latou sini o le faʻaalia i tagata taʻitoʻatasi o loʻo mananaʻo e faia se eseesega i togafitiga faʻapitoa faʻamalosi ma faʻamatalaga malamalama e mafai ona latou tuʻuina atu.