Biologics Mo Ankylosing Spondylitis: El Paso Back Clinic

O le Ankylosing spondylitis ose ma'i afaina e mafua ai le tiga ma le malo o sooga o le tui. I le aluga o taimi, e mafai ona alualu i luma i le fusi o ponaivi o le tui / vetebrae, faʻatapulaʻaina le gaoioi o le tui ma taʻitaʻia ai faʻafitauli faʻaletonu. O le tulaga e sili atu ona taatele i alii ae e aafia ai foi tamaitai. E leai se mafuaaga e iloa, e tasi, ae o tagata taʻitoʻatasi e iai se faʻapitoa gene, HLA-B27, e iai le fa'atuputeleina o le fa'ama'i. Ae ui i lea, o le gene lava ia e le o lona uiga o se tagata e maua i le ankylosing spondylitis; genetics ma isi mea i fafo ma le siosiomaga o loʻo iai foʻi se sao. DMARDs, or Fa'ama'i-Suiga Fua'au Antirheumatic, taofia le mumū. O se togafitiga a le DMARD o lo'o fa'atupula'ia e fa'aogaina ai meaola fa'aola e fa'atatau atili ma taofiofia fa'alavelave fa'apitoa.

Olaola

E le pei o vailaʻau masani, e faʻapipiʻiina, mea olaola e faia mai ma totonu o puna ola.

• E tutupu a'e i aganuu pe selesele mai le toto.
• O mea olaola e lavelave ma taugata.
• Biologics e maua ai nisi o togafitiga sili ona malosi mo le tele o tulaga.
• E lua mea faʻapitoa e masani ona faʻaaogaina e togafitia ai le ankylosing spondylitis o:
• TNF inhibitors.
• IL-17 inhibitors.

TNF Inhibitors

• TNF - tumo necrosis vaega, TNF inhibitors o se vailaʻau faʻaola e taulaʻi ma taofiofia le TNF, lea e aʻafia i faiga faʻafefe i le tino atoa.
• O le polokaina poʻo le taofiofia o le TNF e faʻaitiitia ai le mumū ma e mafai ona faʻatuai ai le alualu i luma o le ankylosing spondylitis.
• E mafai ona faia e ala i se tui po'o se tui e tu'uina atu ai le vaila'au.

Aafiaga itu

O aʻafiaga e fesoʻotaʻi ma lenei vailaʻau, faʻatasi ai ma isi tulaga, e aofia ai:

• Ita o le paʻu – mageso po'o fa'ama'i
• Loto o le fatu
• Lupus
• Lymphoma
• Faʻafitauli e faʻatatau i le neurological system ua lauiloa o fa'aletonu o le fa'ama'i. E mafai ona aofia ai tulaga e pei o:
• Tele sikuea
• Guillain-Barré Syndrome

IL-17 Inhibitors

• IL - interleukin - IL-17 o se porotini o loʻo aʻafia i faiga faʻaleagaina ma tulaga.
• IL-17 inhibitors e taofia le mumū o ni vailaʻau fou ua faʻaalia e manuia ai i latou e maua i le ankylosing spondylitis.
• E masani ona fa'atonu e foma'i IL-17 inhibitors e ala ile tui.

Aafiaga itu

O a'afiaga laiti e aofia ai:

• Headaches
• Sini lanumuli
• Fa'aitaita i le nofoaga o tui.

E sili atu ona ogaoga a'afiaga e aofia ai:

• O nisi o kanesa
• Fa'ama'i pipisi
• Tigā toto maualuga

O isi togafitiga

O sini mo togafitiga mo ankylosing spondylitis e aofia ai:

• Faagesegese le alualu i luma o le faaletonu.
• Faʻaitiitia le mumū.
• Fa'aitiitia le tiga.
• Fa'aleleia po'o le fa'atumauina o so'oga fa'atasi ma le va'aiga o gaio'iga.

O le biologics e le o se togafitiga muamua mo le ankylosing spondylitis.

• E masani ona togafitia muamua e le au tu'uina atu se su'esu'ega muamua i vaila'au fa'ama'i, pei ole NSAIDs, e fa'aitiitia ai le mumu ma fa'agesegese le alualu i luma ole tulaga.
• O le tausiga o le Chiropractic ma le togafitiga faʻale-tino e fautuaina e faʻamautu ma / poʻo le faʻaleleia o le tu, malosi maso, ma le tumau.
• Fautuaina le olaga ma suiga o mea'ai.
• Toleniga fa'atutu ma fa'amalositino.
• Fuafuaga sili ona lelei e fai e fa'auma ai ma le saogalemu ma le mautinoa galuega o aso uma.

Vailaau Fa'aola

Biologics mo ankylosing spondylitis atonu e talafeagai pe leai foi. O nei vaila'au e fa'amoemoe e fesoasoani e fa'amama le mumu e feso'ota'i ma le ma'i ma fa'agesegese le fa'asolosolo o le ma'i. O le a galulue fa'atasi lau 'au tausi soifua maloloina e su'e le filifiliga sa'o mo togafitiga ma fa'amatala fa'amanuiaga, lamatiaga, ma ituaiga o togafitiga. O le a latou mataituina le tulaga, siaki le alualu i luma, ma fetuunai le fuafuaga e tusa ai.

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Iloiloina o le Hormone Therapy

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mau faasino

Ankylosing spondylitis. (nd) National Institute of Arthritis ma Musculoskeletal and Skin Diseases. US Department of Health and Human Services. Avanoa ile: www.niams.nih.gov/health-topics/ankylosing-spondylitis#:~:text=Ankylosing%20spondylitis%20is%20a%20type,the%20spine%20can%20cause%20stiffness (Ausia: Oketopa 12, 2022).

Chen C, Zhang X, Xiao L, Zhang X, Ma X. Faʻatusatusaga Faʻatusatusaga o Faʻatonuga Faʻataʻitaʻiga Faʻapitoa mo Ankylosing Spondylitis: O se Iloiloga Faʻapitoa ma se Faʻasalalauga Meta-Analysis. Fomai (Baltimore). 2016 Mati;95(11):e3060. doi: 10.1097/MD.0000000000003060. PMID: 26986130; PMCID: PMC4839911.

Gerriets V, Goyal A, Khaddour K. Tumor Necrosis Factor Inhibitors. [Fa'afou 2022 Iulai 4]. I totonu: StatPearls [Initaneti]. Treasure Island (FL): StatPearls Publishing; 2022 Ian-. Avanoa mai: www.ncbi.nlm.nih.gov/books/NBK482425/

Lindström, U., Olofsson, T., Wedrén, S. et al. Togafitiga faʻaola o le ankylosing spondylitis: o se suʻesuʻega a le atunuʻu atoa o auala togafitiga i luga o se tulaga maʻi i le falemaʻi. Ga'i Fa'atasi 21, 128 (2019). doi.org/10.1186/s13075-019-1908-9

Yin, Y., Wang, M., Liu, M. et al. Lelei ma le saogalemu o le IL-17 inhibitors mo le togafitiga o le ankylosing spondylitis: o se iloiloga faʻapitoa ma faʻataʻitaʻiga. Ga'i Fa'afitauli 22, 111 (2020). doi.org/10.1186/s13075-020-02208-w