Biochemistry o le DNA Methylation

Faatomuaga i le Methylation

O le methylation, e lauiloa foi o le tasi-carbon metabolism, o se metotia o meaola e mafua ai le gaosiga o le methylation. O se vaega o le methyl, o se tasi o iunite laugatasia masani o tuufaatasiga o meaola ninii, ua faia i luga o le tasi carbon atom ua fusia i tolu hydrogen atom (-CH3). O se vaega o le methyl, faʻaopopo pe aveesea mai faʻamaʻi po o mea faʻaauau, e mafai ona faia i ni auala eseese se lua, e aofia ai:

1. O le faapipiiina o se atigi hydrogen i methylene (-CH2-), e faalauiloa ai le gaosiga o le enzyme methylenetetrahydrofolate reductase, poo le MTHFR. O le oloa o lenei gaioiga e lauiloa o le 5-methylTHF.
2. Le suiga o se vaega o le methyl, e pei o catechol-O-methyltransferase, e lauiloa foi o COMT, ma DNA methyltransferase, e taua foi o le DNMT enzymes. DNA methyltransferase enzymes faaaoga vaega methyl mai S-adenosylmethionine malosi poo SAMe.

E fesuiaʻi SAMe i le S-adenosyl homocysteine, poʻo le SAH, ona faʻaalia lea o le homocysteine ​​i le Ata 1. Homocysteine ​​e mafai foi ona liua i le methionine e ala i se tasi o ala eseese e lua. O le auala iloga, e ala i le liliu mai methionine synthase, e manaʻomia ai le fesuiaiga o se vaega o le methyl mai le 5-methyltetrahydrofolate, poo le 5-MTHF, pe a faia ai e le enzyme methylenetetrahydrofolate reductase, poo le MTHFR, o le enzyme e sili ona lauiloa i ala feoai .

O le ala lona lua mo le biosynthesis methionine mai le homocysteine ​​e auala mai i le homocysteine ​​methyltransferase, lea e tupu i le ate ma fatuga. O le Homocysteine ​​e mafai foi ona amataina se isi auala o meaola, aemaise lava i taimi o setete o le faateleina o le atuatuvale o le oxidative, lea e suia ai le homocysteine ​​i le cystathionine i le taula, glutathione, po o le sulfate. O le auala e faʻafefeteina ai e tumau, ae peitai, ina ia maua ai le glutathione, o le homocysteine ​​e mafai ona faʻaaogaina e maua ai SAMe, i isi auala.

Meaʻai folate mafai ona maua i le tele o meaʻai pei o vailaʻau e taʻua o le pteropolyglutamates. Ina ia mafai ona mitiia lelei, o le polyglutamate e faʻamamaina i totonu o gaʻau i totonu o le monoglutamate lauiloa o tetrahydrofolate poʻo THF. Folic acid, i le isi itu, o le sili ona lauiloa foliga gaosia o le nutrient faʻaaogaina i le faamalosia o meaʻai, e tatau ona faʻaititia e le enzyme dihydrofolate reductase, poʻo le DHFR, faʻalua i le ate o le a manaʻomia ai le faʻaopopoina o lua hydrogen atoms muamua e mafai ona liua i le THF.

O le mea e sili ona taua, o le DHFR gaoioiga e masani lava ona fesuisuiaʻi ma e mafai ona faʻaititia. O le gaoioiga a le DHFR i le ate o le 56 taimi foi lea e faagesegese ai i tagata, e tusa ai ma suʻesuʻega suʻesuʻe, o lona uiga e tatau ona tatou faʻaeteete pe a tatou faʻataunuʻuina fua o le gaosiga o gaʻo i meaola. O le tele lava o taimi, o fomaʻi ma fomaʻi togafitiga o le a faʻaaogaina isi ituaiga o folauga faaopoopo e aofia ai le 5-mTHF ma le folinic acid, poʻo le 10-formyl THF, e aloese ai i se faʻapitoa o le DHFR, ma i le tulaga o le 5-mTHF, ma le faʻamoemoe e puipuia le polymorphism poloka i le MTHFR Enzyme. E tele suʻesuʻega suʻesuʻe na faʻaalia nei suʻesuʻega.

O suʻesuʻega suʻesuʻega faʻatusatusaina o aafiaga o le 5-MTHF ma le siama i luga o le folate ua faʻaalia ai o le methylation e mafai foi ona lelei i le faʻaleleia o le folate levels. Foliniic acid o nisi taimi e faʻaaogaina e lagolago ai le faʻasalaga o le cerebral i nisi tulaga e feaveaʻi ai faʻataʻavalevale i faʻamalosi i le tui o le toto. O le malamalama i le biochemistry o le methylation ua na o le folasaga i le methylation. Meaʻai ma mea faʻaleleia o le olaga ua faʻaalia e fesoasoani i ai methylation lagolago.

Methylation, le fesiitaiga o se methyl group i se tuufaatasiga o meaola, e mafai ona vaevaeina i ni ituaiga faavae se lua: kemikolo ma meaola. O le tulafono faatonutonu o le methylation i le tino o le tagata e faʻalauiloaina e ala i suiga i le DNA ma lena o protein po o enzymes. O le faʻamoemoega o le tusiga o loʻo mulimuli mai o le faʻaalia pe faapefea ona avea le aʻafiaga o vailaʻau ma meaola i le faʻatulagaga o le DNA methylation. O le malamalama i nei faiga e taua i le faʻaleleia atili o le soifua maloloina o le maʻi ma le soifua manuia.

Dr. Alex Jimenez DC, CCST Insight

Smoothies ma Juices for Methylation Support

E ui o le tele o polofesa polofesa mafai fautua faʻatonutonuina o meaʻai ma fesuiaiga olaga, e tele filifiliga faʻafitauli togafitiga e mafai ona e taumafai mo oe lava i le fale. E pei ona faʻamatalaina i luga atu, peitaʻi, o le faʻaopopoga mo le lagolago methylation e tatau ona saʻo ona fuafuaina e se fomaʻi polofesa. Smoothies ma sua o se vave ma faigofie auala e faʻaopopo uma tatau ai mea aoga e te manaʻomia mo le methylation lagolago i le tasi tautua. O lamolemole ma suamalie o loʻo i lalo o se vaega o le Methylation Diet Food Plan.

Sea Green Smoothie
Auaunaga: 1
Cook taimi: 5-10 minute
1/2 XNUMX/XNUMX ipu cantaloupe, kupita
1/2 XNUMX/XNUMX faʻi
'1 limulima o kale poʻo le vasini
1 lima o chard Suiselani
1/4 avoka
'2 sipuni tiina spirulina efuefu
1 ipu vai
3 pe sili atu foʻi ni poloka aisa
Faʻafefiloi mea uma i totonu o se masini eletise maualuga tele seia oʻo ina lelei atoatoa ma fiafia!

Berry Bliss Smoothie
Auaunaga: 1
Cook taimi: 5-10 minute
1/2 XNUMX/XNUMX ipu blueberry (fou pe faʻaaisa, sili ona vao)
1 kaloti feololo, tata lelei
1 XNUMX sipuni palapala eleele flaxseed poʻo chia fatu
1 XNUMX sipuni almonds
'Vai (i le manaʻoga tumau)
Ice Ice cubes (tuu i le faitalia, e mafai ona aveʻese pe a faʻaaogaina blueberry faʻaisa)
Faʻafefiloi mea uma i totonu o se eletise maualuga televavave seia oʻo lava ina malulu ma manaia. E sili ona tautua vave!

Swoona ma le suamalie
Auaunaga: 1
Cook taimi: 5-10 minute
'1 ipu meleni meleni
3 ipu spinach, fufulu
'3 ipu Suiselani chard, fufulu
1 fusi cilantro (laʻau ma 'au), fufulu
1 XNUMX-inisi le faʻamau o le faʻaopoopo, fufuluina, fofo ma tata
2-3 XNUMX-XNUMX knobs atoa laumei lega (tuu i le faitalia), fufulu, fofo ma tata
Faʻaiʻuga mea uma i totonu o se suʻai sili ona maualuga. E sili ona tautua vave!

Ginger Greens Juice
Auaunaga: 1
Cook taimi: 5-10 minute
1 ipu pineapple cubes
1 apu, fasi
1 XNUMX-inisi le faʻamau o le faʻaopoopo, fufuluina, fofo ma tata
3 ipu kale, fufulu ma tata lelei pe masaesae
5 ipu Suiselani chard, fufulu ma tata lelei pe masaesae
Faʻaiʻuga mea uma i totonu o se suʻai sili ona maualuga. E sili ona tautua vave!

Faʻasalaga o le Zesty Beet
Auaunaga: 1
Cook taimi: 5-10 minute
1 grapefruit, peeled ma fasi
1 apu, fufulu ma fasi
1 atoa le pīti, ma ona lau peʻa iai ia oe, mulumulu ma fasi
1 XNUMX-inisi le faʻamau o le faʻaopoopo, fufuluina, fofo ma tata
Faʻaiʻuga mea uma i totonu o se suʻai sili ona maualuga. E sili ona tautua vave!

Protein Power Smoothie
Auaunaga: 1
Cook taimi: minute 5
'1 scoop polotini pauta
'1 sipuni palapala eleele flaxseed
1/2 XNUMX/XNUMX faʻi
Ki 1 kiwi, fofoʻe
1/2 XNUMX/XNUMX sipuniti tiamoni
'Pinch of cardamom
Susu Leai-susu poʻo le vai, lava ia maua ai manaʻoga tumau
Faʻafefiloi mea uma i totonu o se masini eletise eletise seia oʻo lava ina sologa lelei. E sili ona tautua vave!

ProLon Anapogi Mimicking Meaʻai

alualu i luma methylation lagolago e mafai ona maua e ala i meaʻai lelei. O le ProLon` anapogi mimicking taumafataga ofaina se 5-aso taumafataga polokalama ua maeʻa uma ona teuina ma faʻaigoaina e tautua ai meaʻai e te manaʻomia mo le FMD i aofaʻi saʻo ma tuʻufaʻatasiga. O le polokalama taumafataga e faia i le sauni-e-'ai poʻo le faigofie-saunia, mea totino-faʻavae meaai, aofia ai pa, supo, meaʻai mama, faʻaopopoga, o vai inu tuʻufaʻatasia, ma lauti. O oloa e faʻatupuina faʻasaienisi ma tofo lelei. Ae e leʻi amataina le ProLon` anapogi mimicking taumafataga, 5-aso taumafataga polokalama, faʻamolemole ia mautinoa e talanoa i se soifua maloloina polofesa e iloa ai pe o le FMD e talafeagai mo oe. O le ProLon` anapogi mimicking taumafataga mafai ona fesoasoani faʻalauiloa methylation lagolago, faʻatasi ai ma le tele o isi mālōlōina faamanuiaga.

E tele fomaʻi ma fomaʻi togafitiga e mafai ona fautua atu i luga o tui o le methyl donors i le tele o gasegase, peitai, o nisi suʻesuʻega suʻesuʻe e manaʻomia e iloa ai le aofaʻi saʻo ole faaopoopoina ole methylation. O le lautele oa tatou faʻamatalaga e faʻamapulaʻaina i faʻamaʻi faʻamaʻi, muselema ma le popole i mataupu tau le soifua maloloina faapea foi ma tusiga faʻavae, mataupu, ma talanoaga. Ina ia toe talanoaina le mataupu o loʻo i luga, faamolemole ia lagona le saolotoga e fesili atu ia Dr. Alex Jimenez pe faʻafesoʻotaʻi mai i matou 915-850-0900 .

Faʻailoina e Dr. Alex Jimenez

Faʻaopoopo Autu Talanoaga: Matuitui Paʻu Paʻu

Paʻu tua o se tasi o mafuaʻaga sili ona taatele o le le atoatoa ma aso ua misia i galuega i le lalolagi atoa. Faʻasologa o tiga i le mea lona lua e sili ona taatele mo asiasiga o le ofisa o le fomaʻi, naʻo naʻo faʻamaʻi pipisi pito i luga. E tusa ma le 80 pasene o le faitau aofaʻi o le a maua le tiga i le itiiti ifo ma le tasi i le taimi atoa o lo latou olaga. O lau tuila o se fausaga faʻapitoa e faia i ponaivi, sooga, ligaments, ma maso, faatasi ai ma isi mea vaivai. Manua ma / poʻo tulaga faʻamalosia, pei o siaki faʻasolosolo, e mafai ona oʻo atu ai i faʻamaoniga o le tigā mulimuli. O manuʻa o le taʻavale poʻo faʻalavelave faʻafuaseʻi faʻafuaseʻi faʻafuaseʻi o manuʻa e tele lava ina mafua ona o tiga i tua, ae ui i lea, o nisi taimi o le faigofie o gaioiga e mafai ona i ai ni taunuuga tiga. O le mea e lelei ai, o isi togafitiga togafitiga, e pei o le togafitiga o le chiropractic, e mafai ona fesoasoani e faʻafilemu ai le tiga e ala i le faʻaaogaina o fetuunaiga o le ogatotonu ma le faʻaaogaina o le tusi lesona, faʻamalosia ai le faʻamalosi o le tiga.

Fua Faatatau mo le Methylation Support

XYMOGEN's Ole Polokalame Tomai Faapitoa e avanoa e ala i le filifilia o tagata tomai faapitoa ile soifua maloloina. Ole faʻatau ile initaneti ma le faʻaititia o XYMOGEN faʻataʻitaʻiga e matua faʻasaina.

Ma le fiafia, Dr. Alexander Jimenez faia faʻataʻitaʻiga XYMOGEN na o maʻi i lalo o la matou tausiga.

Faʻamolemole valaʻau i le matou ofisa ina ia matou tofia se fomaʻi mo faʻamatalaga vave.

Afai o oe o se tagata maʻi Manua Fomaʻi & Chiropractic Clinic, e mafai ona e fesili e uiga i le XYMOGEN ile valaʻau 915-850-0900.

Mo lou faigofie ma iloiloga o le XYMOGEN oloa faamolemole toe iloilo le sootaga lenei. *XYMOGEN-Catalog-Download

* O tuʻutuʻuga uma o XYMOGEN o loʻo i luga e tumau pea le faʻamalosia.

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