Le Soʻotaga i le va o Meaʻai taumafa ma le Epigenome

O mea taumafa ua avea o se tasi o mea sili ona malamalama lelei i mea tau le siosiomaga e fesoʻotaʻi ma suiga i le epigenome. O meaʻai i mea taumafa tatou te faaaogaina e faʻaleleia e le metabolism ma avea ma malosi. E tasi le auala metabolic, e ui i lea, e nafa ma le gaosia o le methyl group poʻo le epigenetic faʻailoga taua e faʻatonutonu ai o tatou faʻaaliga foliga. O mea taua e taua tele, pei o le B vitamini, SAM-e (S-Adenosyl methionine), ma le folic acid o vaega taua ia i lenei methylation faʻatonuga. O taumafa ma le maualuga o nei meaʻai taua e mafai ona vave suia le faʻatinoina o le mafaufau, aemaise lava ile taimi amata. I le mataupu o sosoo mai, o le a tatou talanoaina le fesoʻotaʻiga i le va o taumafa ma le epigenome.

 

Nutrigenomics ma Soifua Maloloina

 

Talanoaina e fomaʻi, pe a oʻo mai i faʻafitauli tau le soifua maloloina e pei o le afaina ma le tiga tiga, o le malamalama i le nutrigenomics afaina ai lo tatou soifua maloloina e taua. Nutritional genomics, poʻo nutrigenomics, o se saienisi e suʻesuʻeina le fesoʻotaʻiga i le va o taumafa, soifua maloloina, ma le genom. O tagata suʻesuʻe i le nutrigenomics e talitonu o suiga i epigenetic faailoga e mafai ona fesoʻotaʻi ma le tele o mataupu tau le soifua maloloina, e aofia ai le pupuga poʻo le atinaʻeina o faʻamaʻi e pei o le oona, faʻafitauli o fatu, ma kanesa. Suesuega ua faʻaalia mai e ono mafai ona tatou pulea aafiaga o meaʻai tatou te 'aʻai ina ia mafai ai ona suia le faʻaaliga foliga o loʻo fesoʻotaʻi ma isi tulaga tau soifua maloloina.

 

E silia i le 1 mai le 3 tagata matutua i le Iunaite Setete ua maua i le maʻi o le tino lea e iʻu ai ina faʻateleina le ono afaina ai o ni soifua maloloina, e aofia ai ma le prediabetes ma le maʻi suka ituaiga 2, faʻatasi ai ma isi faʻamaʻi. Maeʻa ona suʻesuʻe e faʻaalia ai o suiga i faʻailoga o le epigenetic i le taimi o amata tuputupu aʻe e ono fuafuaina ai tagata taʻitoʻatasi. E le gata i lea, o suiga i faʻailoga ole epigenetic na faʻaalia foi e aʻafia ai auala metabolic e ono faʻaopopoina ai le lamatiaga o prediabetes ma le maʻisuka ituaiga 2. Ua fausia e le au fomaʻi i le nutrigenomics auala fou e mafai ai ona maua le paleni e ala i le malamalama lelei i taumafa ma le epigenome.

 

“O le epigenetic suʻesuʻega e mafai ona maua ai faʻamatalaga e aoga mo fomaʻi. E mafai foʻi ona ofo mai ai ni faʻamatalaga e uiga i le auala o loʻo aafia ai ni mea taua pei o vitamini ma minerale.

 

O le a le Epigenetics Diet?

 

O le upu “epigenetics meaai” na muai fauina e Dr. Trygve Tollefsbol i le 2011. E faʻamatalaina faʻafomai o se vaega o mea, pei o resveratrol i vine mumu, genistein i soya, isothiocyanates i broccoli, ma le tele o isi ituaiga lauiloa o meaʻai, ua faʻaalia e fesoasoani fesoasoani i suiga epigenomic faʻailoga ma Gene faʻaali. E tusa ai ma tagata suʻesuʻe, e mafai e le epigenetics ona taofia le alualu i luma o tuma e ala i le faʻatonutonuina o enzymes e pulea nei epigenomic faʻailoga ma le faʻaali o le gen, e aofia ai le DNA methyltransferases, histone deacetylases, ma nisi RNA e le o ni numera. E tele ituaiga o meaʻai aofia ai le epigenetics meaʻai o loʻo faʻaalia i nei infographic:

 

 

Tagata suʻesuʻe o loʻo faʻaaogaina lata mai tekinolosi faʻaalia e faʻaalia ai le ala e tele bioactive mea mafai ona faateteleina le afaina o le epigenome mafua mai i siosiomaga filogia. I le faʻataʻitaʻiga, o meaʻai faʻaopoopo ma foaʻi methyl, pei o vitamini B12, choline, ma folate, faʻatasi ai ma isi, faʻapea foi ma le isoflavone genistein, e mafai ona faʻatonutonuina suiga i faʻailoga epigenome ma le faʻaaliga o le mafuaʻaga e mafua mai i le bisphenol A, o se hormone-faʻalavelaveina le vailaau . E mafai foi ona puipuia e le B vitamini le leiloa o methylation o le DNA e mafua mai i le ea. Tusa ai ma nei lava suʻesuʻega, o faʻaopoopoga o meaʻai ma le folika acid ua faʻaalia foi e fesoasoani e taofia le le lelei itu-afaina e mafua mai i mamafa uamea.

 

Matou te talitonu o meaʻai i le epigenetics meaʻai e mafai ona faʻaogaina e faʻafetaui ai suiga i le faʻaaliga o foliga ma epigenomic faʻailoga e mafua mai i le siʻosiʻomaga. Siosiomaga mea filogia i le tele o ituaiga o meaʻai, e pei o vailaʻau i fua pei o strawberries ma laulaʻau laugatasi pei o pulu, bisphenol A i totonu o pusa palasitika o meaʻai ma mea inu, dioxins i meaʻai gaʻoa, polycyclic aromatic hydrocarbons gaosia pe a fai aano o manu i luga o le vevela ma ulaula , ma le mekuli ile tele o ituaiga o figota e pei o le mackerel king ma lefishfish, na fesoʻotaʻi ma suiga i suiga epigenomic ma gen gene expression. O na faʻaalia, aemaise lava ile taimi amata amata ona tupu, e ono faʻapogai tele mataupu tau le soifua maloloina.

 

Mo nisi faʻamatalaga e uiga i le fesoʻotaʻiga i le va o meaʻai ma le epigenome, faʻamolemole iloilo lenei tusitusiga:

Taumafa ma le Epigenome

 

O mea taumafa o se tasi o mea sili ona malamalama i mea tau le siosiomaga e fesoʻotaʻi ma suiga o le epigenomic mark and gene expression. O mea taua taua e maua i ituaiga eseese o meaʻai tatou te taumafaina, e faʻaaogaina e suia ma avea ma moli ina ia faʻaaogaina mo le malosi e le tino o le tagata. E tasi le metabolic pathway e gafa ma le fausiaina o methyl group, taua epigenetic faailoga e faʻatonutonu ai o tatou gen gene faʻaaliga ma epigenomic faʻailoga. O mea taua taua e aofia ai ma B vitamini, SAM-e (S-Adenosyl methionine) ma folic acid o vaega taua ia i le DNA methylation. O meaʻai e tele mea ai i nei mea taua e mafai ona vave suia epigenetic faʻailoga ma genes faʻaaliga, aemaise lava i le taimi amata vave. Ma le isi, faʻaopopo le tele o meaʻai lelei i se smoothie mafai ona avea ma faʻavave ma faigofie auala e faʻaopopo ai mea taua mo meaʻai. Lalo o se anapogi ma faigofie smoothie fua e fesoasoani fafagaina ou kenera. - Dr.Alex Jimenez DC, CCST Malamalamaaga

 

 

 

 

Faaopopo Nasturtium i lau Smoothies

 

Faʻaopopoina nasturtium fugalaʻau ma laulaʻau i soʻo se smoothie mafai ona faʻaopopo isi mea taua. O nei mea lelei laʻau e faigofie ona ola ma o le laʻau atoa e maua ai E maualuga le vitamini C i laupepa nasturtium, e taua mo le soifua maloloina lelei, ma o loʻo iai foi le kalisiu, potasium, fosfor, sone, apamemea, ma le uʻamea. E tusa ai ma fomaʻi fomai, o le fua mai i fugalaʻau ma laulaau e iai antimicrobial, antifungal, hypotensive, expectorant, ma anticancer effects. O mea e tutupu i totonu o le togalaʻau nasturtium e tupu ona o le maualuga o ana mea pei o anthocyanins, polyphenols, ma vitamini C. Ona o lona tele o phytochemical mataupu ma tulaga ese o le aoga, o le togalaau nasturtium mafai ona faʻaaogaina i le togafitiga o le tele o mataupu tau soifua maloloina, e aofia ai faʻafitauli i le manava ma le faʻamalositino E le faʻamaninoina, o fugalaʻau ma laulaʻau e matua matagofie lava ile smoothies.

 

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